4-FLUORO-1-NAPHTHALENE CARBOXYLIC ACID - Names and Identifiers
4-FLUORO-1-NAPHTHALENE CARBOXYLIC ACID - Physico-chemical Properties
Molecular Formula | C11H7FO2
|
Molar Mass | 190.17 |
Density | 1.355±0.06 g/cm3(Predicted) |
Melting Point | 224-227 °C (lit.) |
Boling Point | 370.8±15.0 °C(Predicted) |
Flash Point | 178°C |
Vapor Presure | 3.74E-06mmHg at 25°C |
Appearance | Solid |
BRN | 2257292 |
pKa | 3.81±0.10(Predicted) |
Storage Condition | Room Temprature |
MDL | MFCD00004011 |
4-FLUORO-1-NAPHTHALENE CARBOXYLIC ACID - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
HS Code | 29163990 |
Hazard Class | IRRITANT |
4-FLUORO-1-NAPHTHALENE CARBOXYLIC ACID - Introduction
4-fluoro-1-napthoic acid is an organic compound with the chemical formula C11H7FO2. It is a white solid with a special smell. The following is a description of some of the properties, uses, methods and safety information of 4-fluoro-1-napthoic acid:
Nature:
-Appearance: White solid
-Melting point: 142-144 degrees Celsius
-Boiling point: 393 degrees Celsius
-Density: 1.32g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents such as ether and benzene
Use:
4-fluoro-1-napthoic acid can be used as an intermediate in organic synthesis and can be used in the synthesis of other organic compounds. It has important applications in the pharmaceutical and pesticide industries, and is often used in drug synthesis, pigment synthesis and dye synthesis.
Preparation Method:
4-fluoro-1-napthoic acid can be synthesized by the following steps:
1. Add benzyl alcohol and trifluoromethanesulfonic acid in dichloromethane.
2. Add triphosphorus chloride and sulfuric acid at low temperature.
3. The conveying gas is introduced into the reaction system to finally generate 4-fluoro-1-napthoic acid.
Safety Information:
4-fluoro-1-napthoic acid has less impact on human body and environment under general use and storage conditions. But still need to pay attention to the following aspects:
-Avoid direct contact with skin, eyes and respiratory tract as it may be irritating to skin, eyes and mucous membranes.
-Use appropriate personal protective equipment such as gloves, goggles and protective face shields during operation.
-Avoid contact with strong oxidants to avoid dangerous reactions.
-Maintain a well-ventilated place during storage and avoid contact with flammable substances.
Last Update:2024-04-09 19:05:50